Journal article
Cell specificity of transcription regulation by papovavirus T antigens and DNA replication.
Abstract
Simian virus 40 (SV40) and polyomavirus (Py) DNA replication require cellular proteins and a virus‐encoded early gene product, large T antigen (SVT and PyT, respectively). Primate cells contain factors permissive for SV40 replication, whereas murine cells express those factors permissive for Py. We have compared the roles T antigen, cell permissiveness and replication play in transcription of SV40 and Py genes. We show that in their …
Authors
Munholland JM; Kelly JJ; Hassell JA; Wildeman AG
Journal
The EMBO Journal, Vol. 11, No. 1, pp. 177–184
Publisher
Springer Nature
Publication Date
January 1992
DOI
10.1002/j.1460-2075.1992.tb05040.x
ISSN
0261-4189