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Antidepressant Monotherapy vs Sequential...
Journal article

Antidepressant Monotherapy vs Sequential Pharmacotherapy and Mindfulness-Based Cognitive Therapy, or Placebo, for Relapse Prophylaxis in Recurrent Depression

Abstract

CONTEXT: Mindfulness-based cognitive therapy (MBCT) is a group-based psychosocial intervention designed to enhance self-management of prodromal symptoms associated with depressive relapse. OBJECTIVE: To compare rates of relapse in depressed patients in remission receiving MBCT against maintenance antidepressant pharmacotherapy, the current standard of care.

Authors

Segal ZV; Bieling P; Young T; MacQueen G; Cooke R; Martin L; Bloch R; Levitan RD

Journal

JAMA Psychiatry, Vol. 67, No. 12, pp. 1256–1264

Publisher

American Medical Association (AMA)

Publication Date

December 6, 2010

DOI

10.1001/archgenpsychiatry.2010.168

ISSN

2168-622X