Journal article
Development of a Retinoic Acid Receptor-Binding Assay with Rainbow Trout Tissue: Characterization of Retinoic Acid Binding, Receptor Tissue Distribution, and Developmental Changes
Abstract
Retinoic acid (RA) regulates the transcription of various genes required for several essential functions in vertebrates through binding to two classes of nuclear receptors, the retinoic acid receptors (RAR) and retinoid X receptors (RXR). We investigated nuclear RA binding in tissues from rainbow trout using the radiolabeled all-trans and 9-cis isomers of RA. Specific binding (indicative of receptor binding) of both all-trans- and 9-cis-RA was …
Authors
Alsop D; Brown S; Van Der Kraak G
Journal
General and Comparative Endocrinology, Vol. 123, No. 3, pp. 254–267
Publisher
Elsevier
Publication Date
September 2001
DOI
10.1006/gcen.2001.7659
ISSN
0016-6480