Journal article
Association of Interleukin-6 Signalling with the Muscle Stem Cell Response Following Muscle-Lengthening Contractions in Humans
Abstract
BACKGROUND: The regulation of muscle stem cells in humans in response to muscle injury remains largely undefined. Recently, interleukin-6 (IL-6) has been implicated in muscle stem cell (satellite cell)-mediated muscle hypertrophy in animals; however, the role of IL-6 in the satellite cell (SC) response following muscle-lengthening contractions in humans has not been studied.
METHODOLOGY/PRINCIPAL FINDINGS: Eight subjects (age 22+/-1 y; 79+/-8 …
Authors
McKay BR; De Lisio M; Johnston APW; O'Reilly CE; Phillips SM; Tarnopolsky MA; Parise G
Journal
PLOS ONE, Vol. 4, No. 6,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0006027
ISSN
1932-6203