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Radiation-induced DNA damage and the relative...
Journal article

Radiation-induced DNA damage and the relative biological effectiveness of 18F-FDG in wild-type mice

Abstract

Clinically, the most commonly used positron emission tomography (PET) radiotracer is the glucose analog 2-[(18)F] fluoro-2-deoxy-D-glucose ((18)F-FDG), however little research has been conducted on the biological effects of (18)F-FDG injections. The induction and repair of DNA damage and the relative biological effectiveness (RBE) of radiation from (18)F-FDG relative to 662 keV γ-rays were investigated. The study also assessed whether low-dose …

Authors

Taylor K; Lemon JA; Boreham DR

Journal

Mutagenesis, Vol. 29, No. 4, pp. 279–287

Publisher

Oxford University Press (OUP)

Publication Date

July 1, 2014

DOI

10.1093/mutage/geu016

ISSN

0267-8357