The Characterization of a Two Wavelength Time-resolved System for the Determination of Hemoglobin Saturation through Comparison with Continuous Wave and Frequency Domain Systems

The absorption coefficient of hemoglobin is dependent upon its oxygenation status and on the wavelength of interest. The known absorption differences can be used to monitor noninvasively hemoglobin saturation, which is indicative of the oxygenation state of the tissue volume being probed. Time-resolved measurements combined with diffusion theory provide a means of quantifying the optical properties of a turbid medium, like tissue. To …