Journal article
Classification, hepatotoxic mechanisms, and targets of the risk ingredients in traditional Chinese medicine-induced liver injury
Abstract
Traditional Chinese medicine (TCM) has become a crucial cause of drug-induced liver injury (DILI). Differ from chemical medicines, TCM feature more complex and mostly indefinite components. This review aimed to clarify the classification, underlying mechanisms and targets of the risk components in TCM-induced liver injury to further guide the secure application of TCM. Relevant studies or articles published on the PubMed database from January …
Authors
Pan X; Zhou J; Chen Y; Xie X; Rao C; Liang J; Zhang Y; Peng C
Journal
Toxicology Letters, Vol. 323, , pp. 48–56
Publisher
Elsevier
Publication Date
5 2020
DOI
10.1016/j.toxlet.2020.01.026
ISSN
0378-4274