Journal article
Airway autoantibodies are determinants of asthma severity.
Abstract
BACKGROUND: Local airway autoimmune responses may contribute to steroid dependence and persistent eosinophilia in severe asthma. Auto-IgG antibodies directed against granule proteins such as eosinophil peroxidase (EPX), macrophage scavenger receptor with collagenous structure (MARCO) and nuclear/extranuclear antigens (antinuclear antibodies (ANAs)) have been reported. Our objective was to describe the prevalence and clinical characteristics of …
Authors
Salter B; Zhao N; Son K; Tan NS; Dvorkin-Gheva A; Radford K; LaVigne N; Huang C; Kjarsgaard M; Li Q-Z
Journal
European Respiratory Journal, Vol. 60, No. 6,
Publisher
European Respiratory Society (ERS)
Publication Date
12 2022
DOI
10.1183/13993003.00442-2022
ISSN
0903-1936