Manali Mukherjee

Associate Professor, Medicine

0000-0002-7924-7211

Dr. Mukherjee is an Associate Professor in the Division of Respirology, Department of Medicine, and a translational scientist affiliated with the Research Institute of St. Joe's, Hamilton. She has demonstrated expertise in investigating inflammatory mechanisms of chronic respiratory diseases, in particular eosinophils, autoimmunity, response to treatment, and development/validation of clinical biomarkers. Her research has identified the presence of localized autoimmune responses in the airways of patients with complex airways disease and determined their pathogenic role in driving disease severity. Of recent, she has identified autoimmune responses in acute-severe COVID and linked autoimmunity with post-acute COVID-19 sequelae (or Long COVID). In the field of respiratory medicine, she has published over 90 manuscripts (Google Scholar h-index 31, i10-index 55) and had ~ 100 invited speaking engagements since 2020.

Dr. Mukherjee’s research program focuses on “Lung Autoimmunity and Biomarkers." She is the past recipient of the Emerging Researcher Award in Allergic Asthma, awarded conjointly by the Canadian Institutes of Health Research (CIHR) and the Canadian Asthma, Allergy and Immunology Foundation (CAAIF). Her lab is funded by federal and non-federal sources, including CIHR-ICRH and industry. Dr. Mukherjee was recently named the AstraZeneca Chair in Respiratory Diseases (2023-2028) and leads the CIHR-funded national consortium (CanMuc) studying mucus occlusions in severe asthma, COPD, and chronic cough.

Current ongoing projects span from investigating mechanisms of disease to validating biomarkers in asthma, eGPA, COPD, COVID-19, and lung cancer.