Manali Mukherjee

Associate Professor, Medicine

Dr. Mukherjee is an Assistant Professor in the Division of Respirology, Department of Medicine, and a translational scientist affiliated with the Research Institute of St. Joe's, Hamilton. She has demonstrated expertise in investigating inflammatory mechanisms of chronic respiratory diseases, in particular autoimmunity, response to treatment and development/ validation of clinical biomarkers. Her research has identified the presence of localized autoimmune responses in the airways of patients with complex airways disease and determined their pathogenic role in driving disease severity. Of recent, she has identified autoimmune responses in acute-severe COVID and linked autoimmunity with post-acute COVID-19 sequelae (or Long COVID). In the field of respiratory medicine, she published ~65 manuscripts, and in the past 5 years these have accumulated >2000 citations (Google Scholar h-index 23, i10-index 37).

Dr. Mukherjee’s research program focuses on “Lung autoimmunity and biomarkers”. She is the past recipient of the Emerging Researcher Award in Allergic Asthma awarded conjointly by the Canadian Institutes of Health Research (CIHR) and the Canadian Asthma, Allergy and Immunology Foundation (CAAIF). Her lab is funded by federal and non-federal sources including CIHR-ICRH and industry. Dr Mukherjee was recently named the AstraZeneca Chair in Respiratory Diseases (2023-2028).

Current ongoing projects span from investigating mechanisms of disease to validating biomarkers in asthma, eGPA, COVID-19, and lung cancer.