Journal article
Delta-9-tetrahydrocannabinol increases vascular endothelial growth factor (VEGF) secretion through a cyclooxygenase-dependent mechanism in rat granulosa cells
Abstract
While the effects of delta-9-tetrahydrocannabinol (THC), the psychoactive component of cannabis, have been studied extensively in the central nervous system, there is limited knowledge about its effects on the female reproductive system. The aim of this study was to assess the effect of THC on the expression and secretion of the angiogenic factor vascular endothelial growth factor (VEGF) in the ovary, and to determine if these effects were …
Authors
Martínez-Peña AA; Petrik JJ; Hardy DB; Holloway AC
Journal
Reproductive Toxicology, Vol. 111, , pp. 59–67
Publisher
Elsevier
Publication Date
8 2022
DOI
10.1016/j.reprotox.2022.05.004
ISSN
0890-6238