Journal article
A screen of kinase inhibitors reveals a potential role of Chk1 in regulating Hydra head regeneration and maintenance
Abstract
The cnidarian Hydra possesses remarkable regenerative capabilities which allow it to regrow lost or damaged body parts in a matter of days. Given that many key regulators of regeneration and development are evolutionarily conserved, Hydra is a valuable model system for studying the fundamental molecular mechanisms underlying these processes. In the past, kinase inhibitors have been useful tools for determining the role of conserved signaling …
Authors
Lee Y; Muddaluru V; Anwar S; Wilson JY; Campos AR
Journal
The International Journal of Developmental Biology, Vol. 65, No. 10-11-12, pp. 523–536
Publisher
UPV/EHU Press
Publication Date
2021
DOI
10.1387/ijdb.210087yl
ISSN
0214-6282