Journal article
Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation
Abstract
BackgroundGlucocorticoids (GCs) play a pivotal role in fetal programming. Antenatal treatment with synthetic GCs (sGCs) in individuals in danger of preterm labor is common practice. Adverse short- and long-term effects of antenatal sGCs have been reported, but their effects on placental epigenetic characteristics have never been systematically studied in humans.ResultsWe tested the association between exposure to the sGC betamethasone (BET) and …
Authors
Czamara D; Dieckmann L; Röh S; Kraemer S; Rancourt RC; Sammallahti S; Kajantie E; Laivuori H; Eriksson JG; Räikkönen K
Journal
Clinical Epigenetics, Vol. 13, No. 1,
Publisher
Springer Nature
Publication Date
December 2021
DOI
10.1186/s13148-021-01153-y
ISSN
1868-7075