Journal article
The prognostic utility of protein C as a biomarker for adult sepsis: a systematic review and meta-analysis
Abstract
BackgroundSepsis, the dysregulated host response to infection, triggers abnormal pro-coagulant and pro-inflammatory host responses. Limitations in early disease intervention highlight the need for effective diagnostic and prognostic biomarkers. Protein C’s role as an anticoagulant and anti-inflammatory molecule makes it an appealing target for sepsis biomarker studies. This meta-analysis aims to assess the diagnostic and prognostic value of …
Authors
Catenacci V; Sheikh F; Patel K; Fox-Robichaud AE
Journal
Critical Care, Vol. 26, No. 1,
Publisher
Springer Nature
DOI
10.1186/s13054-022-03889-2
ISSN
1364-8535