Journal article
Milvexian for the Prevention of Venous Thromboembolism
Abstract
BACKGROUND: Factor XIa inhibitors for the prevention and treatment of venous and arterial thromboembolism may be more effective and result in less bleeding than conventional anticoagulants. Additional data are needed regarding the efficacy and safety of milvexian, an oral factor XIa inhibitor.
METHODS: In this parallel-group, phase 2 trial, we randomly assigned 1242 patients undergoing knee arthroplasty to receive one of seven postoperative …
Authors
Weitz JI; Strony J; Ageno W; Gailani D; Hylek EM; Lassen MR; Mahaffey KW; Notani RS; Roberts R; Segers A
Journal
New England Journal of Medicine, Vol. 385, No. 23, pp. 2161–2172
Publisher
Massachusetts Medical Society
Publication Date
December 2, 2021
DOI
10.1056/nejmoa2113194
ISSN
0028-4793