Journal article
Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells
Abstract
Triple negative breast cancers (TNBC) are highly aggressive and lack specific targeted therapies. Recent studies have reported high expression of the transcription factor Kaiso in triple negative tumors, and this correlates with their increased aggressiveness. However, little is known about the clinical relevance of Kaiso in the growth and survival of TNBCs. Herein, we report that Kaiso depletion attenuates TNBC cell proliferation, and delays …
Authors
Bassey-Archibong BI; Rayner LGA; Hercules SM; Aarts CW; Dvorkin-Gheva A; Bramson JL; Hassell JA; Daniel JM
Journal
Cell Death & Disease, Vol. 8, No. 3, pp. e2689–e2689
Publisher
Springer Nature
Publication Date
3 2017
DOI
10.1038/cddis.2017.92
ISSN
2041-4889