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Circulating Muramyl Dipeptide Is Negatively...
Journal article

Circulating Muramyl Dipeptide Is Negatively Associated with Interleukin-10 in the Frail Elderly

Abstract

Elevated levels of serum cytokines, a marker of immune activation and chronic inflammation, are commonly associated with age and are a significant risk factor for all-cause mortality in the elderly. This phenomenon is very similar to that exhibited by individuals with diseases of inflammatory etiology and chronic viral infections such as human immunodeficiency virus (HIV). Although the origin of chronically elevated cytokines with age is …

Authors

Verschoor CP; Naidoo A; Wallace JG; Johnstone J; Loeb M; Bramson JL; Bowdish DM

Journal

Inflammation, Vol. 38, No. 1, pp. 272–277

Publisher

Springer Nature

Publication Date

2 2015

DOI

10.1007/s10753-014-0030-z

ISSN

0360-3997