Conference
West Nile Virus Infection: A Model for Human Epitope Immunodominance
Abstract
Cytotoxic lymphocytes (CTL) have been shown to play an important role in the clearance of West Nile Virus (WNV), however no human CTL epitopes have been identified. Using a comparative mass spectrometric approach we identified six HLA‐A*0201 restricted viral‐derived peptides from five different viral proteins (Env, NS2b, NS3, NS4b, and NS5) that are presented during infection. All WNV peptide epitopes were of high affinity for HLA‐A*0201 and …
Authors
McMurtrey C; Schafer F; Bardet W; Buchli R; Eckard A; Piazza P; Hansen T; Bramson J; Rinaldo C; Hildebrand W
Volume
22
Pagination
pp. 855.17-855.17
Publisher
Wiley
Publication Date
3 2008
DOI
10.1096/fasebj.22.1_supplement.855.17
Conference proceedings
The FASEB Journal
Issue
S1
ISSN
0892-6638