Lack of association between type 2 diabetes and major depression: epidemiologic and genetic evidence in a multiethnic population

The positive association between depression and type 2 diabetes (T2D) has been controversial, and little is known about the molecular determinants linking these disorders. Here we investigated the association between T2D and depression at the clinical and genetic level in a multiethnic cohort. We studied 17 404 individuals from EpiDREAM (3209 depression cases and 14 195 controls) who were at risk for T2D and had both phenotypic and genotypic …