Journal article
Genetic manipulation of human embryonic stem cells: a system to study early human development and potential therapeutic applications.
Abstract
The successful derivation of human embryonic stem cell (hESC) lines by Thomson and colleagues [Thomson et al., 1998] provided a new area of investigation in both regenerative medicine and early human development. Fundamental study of the molecular and cellular mechanisms responsible for normal lineage development will rely on reproducible protocols to direct the differentiation of hESCs into specific lineages of interest and genetically …
Authors
Menendez P; Wang L; Bhatia M
Journal
Current Gene Therapy, Vol. 5, No. 4, pp. 375–385
Publisher
Bentham Science Publishers
Publication Date
8 2005
DOI
10.2174/1566523054546198
ISSN
1566-5232