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Journal article

Impact of provincial and national implementation strategies on P2Y12 inhibitor utilization for acute coronary syndrome in the elderly: an interrupted time series analysis from 2008 to 2018

Abstract

BackgroundGuidelines recommend both acetylsalicylic acid and ticagrelor following acute coronary syndrome (ACS), but appropriate prescription practices lag. We analyzed the impact of government medication approval, national guideline updates, and publicly funded drug coverage plans on P2Y12 inhibitor utilization.MethodsAccessing provincial databases, we obtained data for elderly ACS patients in Ontario, Canada, between 2008 and 2018. Using …

Authors

Gupta S; Belley-Cote EP; Eqbal A; McEwen C; Basha A; Wu N; Cerasuolo JO; Mehta S; Schwalm J-D; Whitlock RP

Journal

Implementation Science, Vol. 16, No. 1,

Publisher

Springer Nature

Publication Date

December 2021

DOI

10.1186/s13012-021-01117-z

ISSN

1748-5908