Journal article
Screening of Multiple Biomarkers Associated With Ischemic Stroke in Atrial Fibrillation
Abstract
Background To explore the pathophysiological features of ischemic stroke in patients with atrial fibrillation (AF), we evaluated the association between 268 plasma proteins and subsequent ischemic stroke in 2 large AF cohorts receiving oral anticoagulation. Methods and Results A case-cohort sample of patients with AF from the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) trial, including 282 …
Authors
Hijazi Z; Wallentin L; Lindbäck J; Alexander JH; Connolly SJ; Eikelboom JW; Ezekowitz MD; Granger CB; Lopes RD; Pol T
Journal
Journal of the American Heart Association, Vol. 9, No. 24,
Publisher
Wolters Kluwer
Publication Date
December 15, 2020
DOI
10.1161/jaha.120.018984
ISSN
2047-9980
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Adaptor Proteins, Vesicular TransportAgedAged, 80 and overAnticoagulantsAtrial FibrillationBiomarkersEmbolismFactor Xa InhibitorsFemaleHumansInterleukin-1 Receptor-Like 1 ProteinIschemic StrokeMaleMatrix Metalloproteinase 9Middle AgedNatriuretic Peptide, BrainOsteopontinPatient Outcome AssessmentPeptide FragmentsPyrazolesPyridonesStrokeThromboembolismTrefoil Factor-3