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STAT-6 Is an Absolute Requirement for Murine...
Journal article

STAT-6 Is an Absolute Requirement for Murine Rejection of Hymenolepis diminuta

Abstract

Infection with helminth parasites typically evokes a T helper 2-cell response in the mammalian host. Interleukin (IL)-4 and IL-13 are important in the rapid expulsion of parasitic nematodes, with the absence of either cytokine being compensated for by the other. However, the IL-4 and IL-13 common signaling molecule, signal transducer and activator of transcription 6 (STAT-6) appears to be mandatory for the spontaneous expulsion of enteric …

Authors

McKay DM; Khan WI

Journal

Journal of Parasitology, Vol. 89, No. 1, pp. 188–189

Publisher

American Society of Parasitologists

Publication Date

February 2003

DOI

10.1645/0022-3395(2003)089[0188:siaarf]2.0.co;2

ISSN

0022-3395