Journal article
High-dose versus low-dose angiotensin converting enzyme inhibitors in heart failure: systematic review and meta-analysis
Abstract
OBJECTIVE: To systematically review evidence comparing the effect of low-dose versus high-dose ACE inhibitors (ACEIs) on all-cause and cardiovascular mortality and hospitalisation, functional capacity and side effects in patients with heart failure (HF).
METHODS: We searched PubMed, Embase, Cochrane CENTRAL and LILACS up to January 2019. We included randomised controlled trials (RCTs) comparing low-dose versus high-dose ACEIs in adults with HF …
Authors
Migliavaca CB; Stein C; Colpani V; Eibel B; Bgeginski R; Simões MV; Rohde LE; Falavigna M
Journal
Open Heart, Vol. 7, No. 2,
Publisher
BMJ
Publication Date
August 2020
DOI
10.1136/openhrt-2019-001228
ISSN
2398-595X