Journal article
Red blood cell transfusion and increased length of storage are not associated with deep vein thrombosis in medical and surgical critically ill patients: a prospective observational cohort study
Abstract
IntroductionWith prolonged storage times, cell membranes of red blood cells (RBCs) undergo morphologic and biochemical changes, termed 'RBC storage lesions'. Storage lesions may promote inflammation and thrombophilia when transfused. In trauma patients, RBC transfusion was an independent risk factor for deep vein thrombosis (DVT), specifically when RBC units were stored > 21 days or when 5 or more units were transfused. The objective of this …
Authors
Katsios C; Griffith L; Spinella P; Lacroix J; Crowther M; Hebert P; Meade M; Geerts W; Rabbat C; Cook D
Journal
Critical Care, Vol. 15, No. 6,
Publisher
Springer Nature
Publication Date
2011
DOI
10.1186/cc10526
ISSN
1364-8535