Journal article
Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection
Abstract
Recent studies have reported that COVID-19 patients with lung cancer have a higher risk of severe events than patients without cancer. In this study, we investigated the gene expression of angiotensin I-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) with prognosis in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC). Lung cancer patients in each age stage, subtype, and pathological stage are …
Authors
Kong Q; Xiang Z; Wu Y; Gu Y; Guo J; Geng F
Journal
Molecular Cancer, Vol. 19, No. 1,
Publisher
Springer Nature
Publication Date
December 2020
DOI
10.1186/s12943-020-01209-2
ISSN
1476-4598
Associated Experts
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
Adenocarcinoma of LungAngiotensin-Converting Enzyme 2AnimalsBetacoronavirusCOVID-19Carcinoma, Squamous CellCell LineCoronavirus InfectionsDisease SusceptibilityGene Expression ProfilingGene Expression Regulation, NeoplasticHumansLung NeoplasmsMiceMice, TransgenicPandemicsPeptidyl-Dipeptidase APneumonia, ViralSARS-CoV-2Serine Endopeptidases