Journal article
Efficacy of Donepezil on Behavioral Symptoms in Patients With Moderate to Severe Alzheimer’s Disease
Abstract
OBJECTIVE: This subanalysis of a large, double-blind, placebo-controlled trial examined the prevalence of behavioral symptoms in moderate to severe Alzheimer's disease (AD), and the effect of treatment with donepezil.
METHODS: Two hundred ninety patients with moderate to severe AD (standardized Mini-Mental State Examination scores 5-17) were randomized to receive 24 weeks of once-daily doses of donepezil 5 mg/day for 28 days, and 10 mg/day …
Authors
Gauthier S; Feldman H; Hecker J; Vellas B; Ames D; Subbiah P; Whalen E; Emir B; Group TDMSI
Journal
International Psychogeriatrics, Vol. 14, No. 4, pp. 389–404
Publisher
Elsevier
Publication Date
December 2002
DOI
10.1017/s104161020200858x
ISSN
1041-6102