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Albuminuria and Decline in Cognitive Function: The...
Journal article

Albuminuria and Decline in Cognitive Function: The ONTARGET/TRANSCEND Studies

Abstract

BACKGROUND: Microvascular disease of the kidney (manifesting as albuminuria) and of the brain (manifesting as cognitive decline) may share a common pathogenesis. Gaining an understanding of the concomitant history of these 2 conditions may inform clinical practice and lead to novel prevention and treatment approaches. METHODS: A total of 28 384 participants with vascular disease or diabetes mellitus were examined. At baseline and year 5, …

Authors

Barzilay JI; Gao P; O’Donnell M; Mann JFE; Anderson C; Fagard R; Probstfield J; Dagenais GR; Teo K; Yusuf S

Journal

JAMA Internal Medicine, Vol. 171, No. 2, pp. 142–150

Publisher

American Medical Association (AMA)

Publication Date

January 24, 2011

DOI

10.1001/archinternmed.2010.502

ISSN

2168-6106