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Contemporary trends in high-dose interleukin-2 use...
Journal article

Contemporary trends in high-dose interleukin-2 use for metastatic renal cell carcinoma in the United States

Abstract

BACKGROUND: Targeted therapies (TTs) have revolutionized metastatic renal cell carcinoma (mRCC) treatment in the past decade, largely replacing immunotherapy including high-dose interleukin-2 (HD IL-2) therapy. We evaluated trends in HD IL-2 use for mRCC in the TT era. METHODS: Our cohort comprised a weighted estimate of all patients undergoing HD IL-2 treatment for mRCC from 2004 to 2012 using the Premier Hospital Database. We assessed …

Authors

Allard CB; Gelpi-Hammerschmidt F; Harshman LC; Choueiri TK; Faiena I; Modi P; Chung BI; Tinay I; Singer EA; Chang SL

Journal

Urologic Oncology Seminars and Original Investigations, Vol. 33, No. 11, pp. 496.e11–496.e16

Publisher

Elsevier

Publication Date

November 2015

DOI

10.1016/j.urolonc.2015.06.014

ISSN

1078-1439