Journal article
Combination chemotherapy using high or low dose methotrexate for small cell carcinoma of the lung — A randomised trial
Abstract
Eighty-three patients with histologically proven small cell carcinoma of the lung were entered into a prospective randomised clinical trial to evaluate two induction regimes. A ‘low’ dose methotrexate regime which employed three cycles of etoposide, adriamycin and methotrexate given at conventional dosage was compared with a regime which employed three cycles of etoposide and adriamycin together with five courses of high dose methotrexate and …
Authors
Arnold AM; Williams CJ; Mead GM; Buchanan RB; Green JA; Macbeth FM; Whitehouse JM
Journal
Medical Oncology, Vol. 1, No. 1, pp. 9–14
Publisher
Springer Nature
Publication Date
March 1984
DOI
10.1007/bf02935319
ISSN
1357-0560