Micropatterning of functional lipid domains for toxin detection

We present a method for patterning receptor-populated lipid domains at the micrometer scale. The receptors contained in these domains are functional and can bind toxin fragments, thus serving as potential components of biosensors. To pattern the lipid domains we have made use of a novel micro-patterning technique, which involves the etching of a polymer coating to expose specific areas of a silicon substrate [1]. The chip is then incubated with …