Journal article
Prognostic value of the trichorhinophalangeal syndrome-1 (TRPS-1), a GATA family transcription factor, in early-stage breast cancer
Abstract
BACKGROUND: TRPS-1 is a new GATA transcription factor that is differentially expressed in breast cancer (BC) where it been found recently to regulate epithelial-to-mesenchymal transition (EMT).
PATIENTS AND METHODS: We carried out a quantitative immunohistochemistry (qIHC) analysis of TRPS-1 expression in 341 primary-stage I-III BC samples in relation to patient clinical characteristics as well as its prognostic value, especially in an estrogen …
Authors
Chen JQ; Bao Y; Lee J; Murray JL; Litton JK; Xiao L; Zhou R; Wu Y; Shen XY; Zhang H
Journal
Annals of Oncology, Vol. 24, No. 10, pp. 2534–2542
Publisher
Elsevier
Publication Date
October 2013
DOI
10.1093/annonc/mdt190
ISSN
0923-7534
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAgedAged, 80 and overBiomarkers, TumorBreast NeoplasmsCadherinsCarcinoma, Ductal, BreastDNA-Binding ProteinsDisease-Free SurvivalEpithelial-Mesenchymal TransitionEstrogen Receptor alphaFemaleGene Expression ProfilingHumansImmunohistochemistryKi-67 AntigenMiddle AgedReceptor, ErbB-2Receptors, ProgesteroneRepressor ProteinsTranscription Factors