Journal article
Nonautologous gene therapy with implantable devices
Abstract
Treatment of human diseases with gene therapy is a technological break through that has been touted to be the "ultimate medicine". A potentially more cost-effective method of gene therapy is to use universal cell lines engineered to secrete therapeutic products that are suitable for implantation in all patients requiring the same product replacement. To avoid immune rejection, these nonautologous donor cells can be protected within …
Authors
Chang PL
Journal
IEEE Pulse, Vol. 16, No. 5, pp. 145–150
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Publication Date
1997
DOI
10.1109/51.620507
ISSN
2154-2287
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AnimalsBiocompatible MaterialsCapsulesCells, CulturedDisease Models, AnimalFactor IXGene Expression RegulationGenetic Diseases, InbornGenetic TherapyGrowth HormoneHuman Growth HormoneImplants, ExperimentalLysosomal Storage DiseasesMethylmethacrylatesMiceMolecular WeightPermeabilityPolyhydroxyethyl MethacrylateProstheses and ImplantsProteinsRecombinant ProteinsTransfection