Journal article
Characterization of Radioprotective, Radiomitigative and Bystander Signaling Modulating Effects of Endogenous Metabolites Phenylacetate, Ursodeoxycholate and Tauroursodeoxycholate on HCT116 Human Colon Carcinoma Cell Line
Abstract
Exposures to ionizing radiation can cause depletion in stem cell reservoirs and lead to chronic injury processes that exacerbate carcinogenic and inflammatory responses. Therefore, radioprotective measures, against both acute and chronic biological effects of radiation, require frequent intake of nontoxic natural products, which have practical oral administration. The goal of this study was to characterize the radioprotective, radiomitigative …
Authors
Vukmirovic D; Vo NTK; Seymour C; Rollo D; Mothersill C
Journal
Radiation Research, Vol. 192, No. 1, pp. 28–39
Publisher
Radiation Research Society
Publication Date
July 2019
DOI
10.1667/rr15323.1
ISSN
0033-7587