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Imputation of missing genotypes: an empirical...
Journal article

Imputation of missing genotypes: an empirical evaluation of IMPUTE

Abstract

BackgroundImputation of missing genotypes is becoming a very popular solution for synchronizing genotype data collected with different microarray platforms but the effect of ethnic background, subject ascertainment, and amount of missing data on the accuracy of imputation are not well understood.ResultsWe evaluated the accuracy of the program IMPUTE to generate the genotype data of partially or fully untyped single nucleotide polymorphisms …

Authors

Zhao Z; Timofeev N; Hartley SW; Chui DH; Fucharoen S; Perls TT; Steinberg MH; Baldwin CT; Sebastiani P

Journal

BMC Genomic Data, Vol. 9, No. 1,

Publisher

Springer Nature

Publication Date

December 2008

DOI

10.1186/1471-2156-9-85

ISSN

1471-2156