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Phase II Trial of Radiosurgery to Magnetic...
Journal article

Phase II Trial of Radiosurgery to Magnetic Resonance Spectroscopy–Defined High-Risk Tumor Volumes in Patients With Glioblastoma Multiforme

Abstract

PURPOSE: To determine the efficacy of a Gamma Knife stereotactic radiosurgery (SRS) boost to areas of high risk determined by magnetic resonance spectroscopy (MRS) functional imaging in addition to standard radiotherapy for patients with glioblastoma (GBM). METHODS AND MATERIALS: Thirty-five patients in this prospective Phase II trial underwent surgical resection or biopsy for a GBM followed by SRS directed toward areas of MRS-determined high …

Authors

Einstein DB; Wessels B; Bangert B; Fu P; Nelson AD; Cohen M; Sagar S; Lewin J; Sloan A; Zheng Y

Journal

International Journal of Radiation Oncology • Biology • Physics, Vol. 84, No. 3, pp. 668–674

Publisher

Elsevier

Publication Date

November 2012

DOI

10.1016/j.ijrobp.2012.01.020

ISSN

0360-3016