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Mitogenic Properties of Polyene Antibiotics for...
Journal article

Mitogenic Properties of Polyene Antibiotics for Murine B Cells

Abstract

Two polyene antibiotics, nystatin and amphotericin B, were found to be mitogenic for mouse spleen cells as measured by induction of DNA synthesis and polyclonal antibody production. This effect was demonstrated on spleen cells from nude mice and anti-theta-treated spleen cells from normal mice. No effect was found on cortisone-resistant thymocytes or on spleen cells treated with anti-mouse bone marrow-derived lymphocyte antigen antiserum. Nor …

Authors

HAMMARSTRÖM L; SMITH E

Journal

Scandinavian Journal of Immunology, Vol. 5, No. 1‐2, pp. 37–43

Publisher

Wiley

Publication Date

1 1976

DOI

10.1111/j.1365-3083.1976.tb02990.x

ISSN

0300-9475