Clinical Outcomes of Failing to Dose-Reduce Cephalosporin Antibiotics in Older Adults with CKD

Abstract

BACKGROUND AND OBJECTIVES: Current dosing recommendations for cephalosporin antibiotics are on the basis of pharmacokinetic studies and are frequently ignored in practice. This study was undertaken to investigate the clinical outcomes of failing to dose-reduce cephalosporin antibiotics in CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Retrospective cohort study conducted in Ontario, Canada using linked population-based health care …

Authors

Bathini L; Jandoc R; Kuwornu P; McArthur E; Weir MA; Sood MM; Battistella M; Muanda FT; Liu A; Jain AK

Journal

Clinical Journal of the American Society of Nephrology, Vol. 14, No. 2, pp. 197–205

Publisher

Wolters Kluwer

Publication Date

February 2019

DOI

10.2215/cjn.10710918

ISSN

1555-9041

Associated Experts

Amit Garg

Assistant Professor (Part-Time), Faculty of Health Sciences

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