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Anti-NT5c1A Autoantibodies as Biomarkers in...
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Anti-NT5c1A Autoantibodies as Biomarkers in Inclusion Body Myositis

Abstract

Objective: Sporadic Inclusion Body Myositis (sIBM) is an inflammatory myopathy (IIM) without a specific diagnostic biomarker until autoantibodies to the cytosolic 5'-nucleotidase 1A (NT5c1A/Mup44) were reported. The objectives of our study were to determine the sensitivity and specificity of anti-NT5c1A for sIBM, demonstrate demographic, clinical and serological predictors for anti-NT5c1A positivity and determine if anti-nuclear antibody (ANA) …

Authors

Amlani A; Choi MY; Tarnopolsky M; Brady L; Clarke AE; La Torre IG-D; Mahler M; Schmeling H; Barber CE; Jung M

Volume

10

Publisher

Frontiers

DOI

10.3389/fimmu.2019.00745

Conference proceedings

Frontiers in Immunology

ISSN

1664-3224