Journal article
Dosing Efficiency and Particle-size Characteristics of Pressurized Metered-dose Inhaler Aerosols in Narrow Catheters
Abstract
An experimental in vitro model was used to determine the effects of intraluminal catheter diameter and length on the delivered dose and particle-size characteristics of salbutamol (albuterol) aerosol delivered by metered dose inhaler (MDI) (Ventolin, 100 micrograms per puff). The dose of aerosolized drug that exited a 16-cm-long tracheal tube with an inner diameter (ID) of 6 mm was compared with that from 4 catheters of differing diameters and …
Authors
Taylor RH; Lerman J; Chambers C; Dolovich M
Journal
Chest, Vol. 103, No. 3, pp. 920–924
Publisher
Elsevier
Publication Date
3 1993
DOI
10.1378/chest.103.3.920
ISSN
0012-3692