Conference
Abstract B092: Therapeutic targeting of tumorigenic EphA2+/EphA3+ brain tumor initiating cells with bi-specific antibody in glioblastoma
Abstract
Abstract
Glioblastoma (GBM), the most aggressive primary human brain tumor, carrier a dismal prognosis and is increasingly characterized by cellular and genetic intra-tumoral heterogeneity (ITH). Many of the 14 members of the erythropoietin-producing hepatocellular carcinoma receptor (EphR) family and their ephrin ligands are expressed in GBM cells and constitute potential molecular targets for novel therapeutic agents. We …
Authors
Vora P; Qazi M; Chokshi C; Venugopal C; London M; Hu A; McFarlane N; Subapanditha M; Singh M; Mahendram S
Volume
4
Pagination
pp. b092-b092
Publisher
American Association for Cancer Research (AACR)
Publication Date
November 1, 2016
DOI
10.1158/2326-6066.imm2016-b092
Conference proceedings
Cancer Immunology Research
Issue
11_Supplement
ISSN
2326-6066