Journal article
Efficacy of Secretagogues in Patients With Irritable Bowel Syndrome With Constipation: Systematic Review and Network Meta-analysis
Abstract
BACKGROUND & AIMS: Several secretagogues have been approved for the treatment of irritable bowel syndrome with constipation (IBS-C). However, their relative efficacy is unclear because there have been no head-to-head randomized controlled trials. We conducted a network meta-analysis to compare their efficacies in patients with IBS-C.
METHODS: We searched MEDLINE, EMBASE, EMBASE Classic, and the Cochrane Central Register of Controlled Trials …
Authors
Black CJ; Burr NE; Quigley EMM; Moayyedi P; Houghton LA; Ford AC
Journal
Gastroenterology, Vol. 155, No. 6, pp. 1753–1763
Publisher
Elsevier
Publication Date
December 2018
DOI
10.1053/j.gastro.2018.08.021
ISSN
0016-5085