Journal article
Quantification of Human Tissue Kallikreins in the Stratum Corneum: Dependence on Age and Gender
Abstract
Human tissue kallikreins are a family of 15 trypsin or chymotrypsin-like secreted serine proteases (hK1-hK15). hK5, hK6, hK7, hK8, and hK13 have been identified in the stratum corneum (SC), stratum granulosum, and skin appendages. It has been reported that hK5 and hK7 degrade desmosomes/corneodesmosomes, suggesting that kallikreins are responsible for desquamation. We report the quantification of hK5, hK6, hK7, hK8, hK10, hK11, hK13, and hK14 …
Authors
Komatsu N; Saijoh K; Sidiropoulos M; Tsai B; Levesque MA; Elliott MB; Takehara K; Diamandis EP
Journal
Journal of Investigative Dermatology, Vol. 125, No. 6, pp. 1182–1189
Publisher
Elsevier
Publication Date
December 2005
DOI
10.1111/j.0022-202x.2005.23933.x
ISSN
0022-202X