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How low can you go: What is the safe threshold for...
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How low can you go: What is the safe threshold for platelet transfusions in patients with hematologic malignancy in sub-Saharan Africa

Abstract

BACKGROUND: Despite the importance of platelet transfusions in treatment of hematologic cancer patients, the optimal platelet count threshold for prophylactic transfusion is unknown in sub-Saharan Africa. METHODS: We followed patients admitted to the Uganda Cancer Institute with a hematological malignancy in 3 sequential 4-month time-periods using incrementally lower thresholds for prophylactic platelet transfusion: platelet counts ≤ 30 x 109/L …

Authors

Ddungu H; Krantz EM; Kajja I; Naluzze S; Nabbanja H; Nalubwama F; Phipps W; Orem J; Kiwanuka N; Wald A

Volume

14

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0211648

Conference proceedings

PLOS ONE

Issue

2

ISSN

1932-6203