Journal article
Rapid transepithelial antigen transport in rat jejunum: Impact of sensitization and the hypersensitivity reaction
Abstract
BACKGROUND & AIMS: Intestine from sensitized rats develops a rapid secretory response to luminal antigen challenge that depends on activation of subepithelial mast cells. The aim of this study was to determine the timing and route of the transepithelial protein antigen transport.
METHODS: Rats were sensitized to horseradish peroxidase (HRP). After 10-14 days, jejunal segments were resected, mounted in Ussing chambers, and challenged with HRP on …
Authors
Berin M; Kiliaan A; Yang P; Groot J; Taminiau J; Perdue M
Journal
Gastroenterology, Vol. 113, No. 3, pp. 856–864
Publisher
Elsevier
Publication Date
9 1997
DOI
10.1016/s0016-5085(97)70180-x
ISSN
0016-5085