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Escalated as Compared with Standard Doses of...
Journal article

Escalated as Compared with Standard Doses of Doxorubicin in BACOP Therapy for Patients with Non-Hodgkin's Lymphoma

Abstract

BACKGROUND AND METHODS: In 1981 the Clinical Trials Group of the National Cancer Institute of Canada completed a pilot study in patients with advanced-stage non-Hodgkin's lymphoma with aggressive tumor histology. That study demonstrated the potential efficacy of escalating the dose of doxorubicin used in a regimen of bleomycin, doxorubicin, cyclophosphamide, vincristine, and prednisone (BACOP). In the present study, we compared standard BACOP …

Authors

Meyer RM; Quirt IC; Skillings JR; Cripps MC; Bramwell V; Weinerman BH; Gospodarowicz MK; Burns BF; Sargeant AM; Shepherd LE

Journal

New England Journal of Medicine, Vol. 329, No. 24, pp. 1770–1776

Publisher

Massachusetts Medical Society

Publication Date

December 9, 1993

DOI

10.1056/nejm199312093292404

ISSN

0028-4793