Journal article
The association between HLA‐DQB1 polymorphism and antituberculosis drug‐induced liver injury: a Case–Control Study
Abstract
WHAT IS KNOWN AND OBJECTIVE: Research on genetic factors associated with antitubercular drug-induced liver injuries (ATLI) has been reported. However, most of the research has focused on genetic polymorphisms of genes encoding metabolic enzymes, including NAT2, GST and CYP450. It is probable that the immune system also contributes to the onset of drug adverse effects. A few small studies have explored the possible association of HLA genes with …
Authors
Chen R; Zhang Y; Tang S; Lv X; Wu S; Sun F; Xia Y; Zhan SY
Journal
Journal of Clinical Pharmacy and Therapeutics, Vol. 40, No. 1, pp. 110–115
Publisher
Hindawi
Publication Date
February 2015
DOI
10.1111/jcpt.12211
ISSN
0269-4727