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Denosumab versus risedronate in...
Journal article

Denosumab versus risedronate in glucocorticoid-induced osteoporosis: a multicentre, randomised, double-blind, active-controlled, double-dummy, non-inferiority study

Abstract

BACKGROUND: Glucocorticoid-induced osteoporosis is the most common form of secondary osteoporosis and is associated with an estimated annual fracture rate of 5%. We aimed to assess the efficacy and safety of denosumab compared with risedronate in glucocorticoid-induced osteoporosis. METHODS: We did a 24-month, double-blind, active-controlled, double-dummy, non-inferiority study at 79 centres in Europe, Latin America, Asia, and North America. …

Authors

Saag KG; Wagman RB; Geusens P; Adachi JD; Messina OD; Emkey R; Chapurlat R; Wang A; Pannacciulli N; Lems WF

Journal

The Lancet Diabetes & Endocrinology, Vol. 6, No. 6, pp. 445–454

Publisher

Elsevier

Publication Date

6 2018

DOI

10.1016/s2213-8587(18)30075-5

ISSN

2213-8587