Journal article
Microfluidic-based electrotaxis for on-demand quantitative analysis of Caenorhabditis elegans' locomotion.
Abstract
The nematode Caenorhabditis elegans is a versatile model organism for biomedical research because of its conservation of disease-related genes and pathways as well as its ease of cultivation. Several C. elegans disease models have been reported, including neurodegenerative disorders such as Parkinson's disease (PD), which involves the degeneration of dopaminergic (DA) neurons (1). Both transgenes and neurotoxic chemicals have been used to …
Authors
Tong J; Rezai P; Salam S; Selvaganapathy PR; Gupta BP
Journal
Journal of Visualized Experiments, , No. 75,
Publisher
MyJove
DOI
10.3791/50226
ISSN
1940-087X