Journal article
Randomized Trial of Hyperfractionation Versus Conventional Fractionation in T2 Squamous Cell Carcinoma of the Vocal Cord (RTOG 9512)
Abstract
PURPOSE: To compare hyperfractionation versus standard fractionation for T2N0 vocal cord carcinoma in a randomized controlled trial.
METHODS AND MATERIALS: Patients with T2 vocal cord cancer were stratified by substage (T2a vs T2b) and randomly assigned to receive either hyperfractionation (HFX) to 79.2 Gy in 66 fractions of 1.2 Gy given twice a day, or standard fractionation (SFX) to 70 Gy in 35 fractions given once a day. The trial was …
Authors
Trotti A; Zhang Q; Bentzen SM; Emami B; Hammond ME; Jones CU; Morrison WH; Sagar SM; Ridge JA; Fu KK
Journal
International Journal of Radiation Oncology • Biology • Physics, Vol. 89, No. 5, pp. 958–963
Publisher
Elsevier
Publication Date
August 2014
DOI
10.1016/j.ijrobp.2014.04.041
ISSN
0360-3016