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Oxidized Phospholipids, Lipoprotein(a), and...
Journal article

Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis

Abstract

BACKGROUND: Elevated lipoprotein(a) (Lp[a]) is associated with aortic stenosis (AS). Oxidized phospholipids (OxPL) are key mediators of calcification in valvular cells and are carried by Lp(a). OBJECTIVES: This study sought to determine whether Lp(a) and OxPL are associated with hemodynamic progression of AS and AS-related events.

Authors

Capoulade R; Chan KL; Yeang C; Mathieu P; Bossé Y; Dumesnil JG; Tam JW; Teo KK; Mahmut A; Yang X

Journal

Journal of the American College of Cardiology, Vol. 66, No. 11, pp. 1236–1246

Publisher

Elsevier

Publication Date

9 2015

DOI

10.1016/j.jacc.2015.07.020

ISSN

0735-1097